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Cell surface glycan engineering of neural stem cells augments neurotropism...

Merzaban JS, Imitola J, Starossom SC, Zhu B, Wang Y, Lee J, Ali AJ, Olah M, Abuelela AF, Khoury SJ, Sackstein R. Glycobiology. 2015 Dec;25(12):1392-409. doi: 10.1093/glycob/cwv046. PMID: 26153105...

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Novel mechanisms of platelet clearance and thrombopoietin regulation

Grozovsky R, Giannini S, Falet H, Hoffmeister KM. Curr Opin Hematol. 2015 Sep;22(5):445-51. doi: 10.1097/MOH.0000000000000170. Review. PMID: 26154508 Abstract PURPOSE OF REVIEW: The human body produces...

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Desialylation is a mechanism of Fc-independent platelet clearance and a...

Li J, van der Wal DE, Zhu G, Xu M, Yougbare I, Ma L, Vadasz B, Carrim N, Grozovsky R, Ruan M, Zhu L, Zeng Q, Tao L, Zhai ZM, Peng J, Hou M, Leytin V, Freedman J, Hoffmeister KM, Ni H. Nat Commun. 2015...

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2015 proceedings of the National Heart, Lung, and Blood Institute’s State of...

Spitalnik SL, Triulzi D, Devine DV, Dzik WH, Eder AF, Gernsheimer T, Josephson CD, Kor DJ, Luban NL, Roubinian NH, Mondoro T, Welniak LA, Zou S, Glynn S; State of the Science in Transfusion Medicine...

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Regulating billions of blood platelets: glycans and beyond

Grozovsky R, Giannini S, Falet H, Hoffmeister KM. Blood. 2015 Oct 15;126(16):1877-84. doi: 10.1182/blood-2015-01-569129. Review. PMID: 26330242 Abstract The human body produces and removes 10(11)...

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Fulfilling Koch’s postulates in glycoscience: HCELL, GPS and translational...

Sackstein R. Glycobiology. 2016 Jun;26(6):560-70. doi: 10.1093/glycob/cww026. Review. PMID: 26933169 Abstract Glycoscience-based research that is performed expressly to address medical necessity and...

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Glycans and the platelet life cycle

Li R, Hoffmeister KM, Falet H. Platelets. 2016 Sep;27(6):505-11. doi: 10.3109/09537104.2016.1171304. PMID: 27135356 Abstract Platelet numbers are intricately regulated to avoid spontaneous bleeding or...

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Platelet clearance by the hepatic Ashwell-Morrell receptor: mechanisms and...

Hoffmeister KM, Falet H. Thromb Res. 2016 May;141 Suppl 2:S68-72. doi: 10.1016/S0049-3848(16)30370-X. PMID: 27207430 Abstract The daily production of billions of platelets must be regulated to avoid...

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Glycoengineering of E-Selectin Ligands by Intracellular versus Extracellular...

Dykstra B, Lee J, Mortensen LJ, Yu H, Wu ZL, Lin CP, Rossi DJ, Sackstein R. Stem Cells. 2016 Oct;34(10):2501-2511. doi: 10.1002/stem.2435. PMID: 27335219 Abstract Human mesenchymal stem cells (MSCs)...

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Tumorigenic potential is restored during differentiation in...

Yao J, Zhang L, Hu L, Guo B, Hu X, Borjigin U, Wei Z, Chen Y, Lv M, Lau JT, Wang X, Li G, Hu YP. Cell Death Dis. 2016 Jul 28;7(7):e2314. doi: 10.1038/cddis.2016.189. PMID: 27468690 Abstract Detailed...

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